Investigation

Discovered new ways to combat debilitating autoimmune diseases

Researchers from the British Bristol University today announced a major breakthrough in the fight against the debilitating autoimmune diseases, namely multiple sclerosis, to reveal how cells stop attacking the fabric of a healthy body.

Today, ScienceDaily reports that the magazine's team of researchers has discovered how to convert cells that act as aggressors in protective against disease. According to scientific publication, This is a discovery which could lead to widespread use of antigen specific immunotherapy – substance that stimulates the production of antibodies against aggressions – for the treatment of many autoimmune diseases, including multiple sclerosis (MS), diabetes type 1, Graves' disease, and SLE (THE).

For the researcher David Wraith, who led the research, “understanding the molecular basis of antigen specific immunotherapy opens exciting new opportunities to increase the selectivity of the approach to provide valuable markers to measure effective treatment. These findings have important implications for many patients suffering from difficult diseases to treat autoimmune”.

A team of researchers from the University of Bristol showed how the administration of protein fragments that are usually the target for attack leads to correction of the autoimmune response, in which cells react against the body's own.

This type of conversion has been applied to allergies, known as “allergy desensitization”, but its application to autoimmune diseases have been made only recently.

Source: Lusa, Lisbon 3 September 2014

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